Optimal Medical Therapy with or without PCI for Stable Coronary Disease, William E. Boden, M.D.,and others, NEJM april 12, 2007. This study was performed to evaluate and compare optimal medical therapy with percutaneous coronary intervention (PCI). In patients with stable coronary artery disease, it remains unclear whether an initial management strategy of percutaneous coronary intervention (PCI), combined with intensive pharmacologic therapy …