The FAME 1&2 Trials

Dr TPapers, Professionals

In 1995 Topol[1] first described what vascular surgeons have known for many years: The pressure drop in a fluid flowing through a long cylindrical pipe such as a stenotic artery becomes functionally significant when the obstruction exceeds 70%, first described in the Poiseuille law in 1846[2]. As was stated in Topol’s paper: “Accordingly, before the residual stenosis in an infarct …